사업성과

연구성과

[논문] Self-Healing and Thermal Responsive DNA Bioplastics for On-Demand Degradable Medical Devices
2024-04-01
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유전성 췌장염 예방을 위한 가이드 RNA 나노입자-마이크로버블 복합체를 통한 초음파 감응형 유전자 편집 전달체 기술 개발

연구책임자 : 서강대학교 김현철 교수



Recently, there has been a growing demand for the development of biomass-based plastic materials as a solution to address the pressing issue of accumulated plastic waste. 

Alongside biodegradable plastics derived from petroleum and organisms, DNA-based materials have emerged as potential substitutes for nonbiodegradable plastics. 

Here, we introduce DNA Bioplastics that are synthesized through a one-pot process involving DNA and a cross-linker. 

These DNA Bioplastics exhibit key characteristics that closely resemble conventional plastic materials, including thermal-responsive volumetric transition, thermoplasticity, and solidification, leveraging the inherent properties of DNA.

By manipulating the cross-linking density of DNA Bioplastic during the reaction, we have successfully demonstrated the ability to achieve a wide range of desirable physical properties. 

The versatility of DNA as a renewable source and the eco-friendly disposal options for DNA Bioplastics open up new avenues for the disposable bioplastic materials, including disposable medical devices. 



ACS Materials Letters (2024)


https://pubs.acs.org/doi/10.1021/acsmaterialslett.3c01648 

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